CTS-V includes sophisticated braking and tire systems, in partnership with two companies renowned for high-performance technology: Brembo and Michelin. Brembo brakes are at all four corners and include powerful, six-piston calipers in the front and four-piston calipers in the rear.

Slotted and vented rotors enable strong initial braking force while optimizing heat resistance and eliminating fade. The brake rotors from Brembo employ a "dual-cast" technology that combines cast iron and aluminum, resulting in excellent performance and weight reduction. CTS-V also includes an electric parking brake, enabling more legroom for the driver, key for high-performance driving.

Michelin partnered with Cadillac engineers to develop its acclaimed Pilot Sport PS2 summer tire for Cadillac CTS-V and its exclusive 19-inch alloy wheels. The tires support high levels of grip in track conditions, while also affording good performance on the road.